Dave welcomes actor Denis Leary, actress Olivia Wilde, and musical guests The Pierces. The San Francisco Giants perfect game pitcher presents the "Top Ten Things I Want To Achieve Now That I've Thrown A Perfect Game". Denis has come up with the next killer app idea. Olivia and boyfriend Jason Sudeikis went to Jamaica, but it turned into a bad Japanese game show. The duo from Alabama performs "You'll Be Mine" from their album, "You & I."