Following the bludgeoning to death of a nurse, Hooker and co. investigate the case, the latest in a series of similar murders - a string of killings that Hooker investigated years before that has recently began again, in which the attacker sends a rose to the intended victim prior to the attack. With the aid of a disabled veteran detective and a top psychiatrist, Hooker and the team investigate and find evidence that the murderer, always dressed as an old-fashioned nurse, may actually be a man. But the pattern of the killings suggests that they have less than 48 hours to catch the killer before he / she strikes again.